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Friday, April 27 • 9:10am - 9:50am
Advances in Basic and Clinical Immunology 2018

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The management of IMIDs requires the integration of the latest advances in basic, translational, and clinical immunology into targeted therapeutic strategies. To guide this process, success stories from aligned fields can be used to increase our understanding of disease pathology and improve the quality of care.

For example, recent progress in the primary immunodeficiency field has clarified that many of these disorders present with autoimmune manifestations, and elucidation of the biologic underpinnings of these conditions has led to the development of targeted therapies. Noteworthy immunologic advances have also been achieved in the field of oncology, with the emergence of immunologic checkpoint inhibitors hailed as one of the most significant advances in biomedicine over the past five years.

However, these checkpoint inhibitors have also generated new clinical challenges in their potential for immunologic adverse effects, which require prompt intervention to ensure continued patient adherence and positive outcomes.

Finally, chimeric antigen receptor (CAR) T cells represent the cutting edge in oncology treatment and are poised to rapidly transform this field in the near future. Overall, the outlook for immunologic and inflammatory medicine appears bright, with movement toward individualized therapeutic strategies offering new hope for improved outcomes. 

Speakers
avatar for Leonard H. Calabrese, DO

Leonard H. Calabrese, DO

Professor of Medicine, Cleveland Clinic Lerner College of Medicine, Case Western University; R.J. Fasenmyer Chair of Clinical Immunology, Cleveland Clinic
Leonard H. Calabrese, DO, heads Cleveland Clinic's Section of Clinical Immunology and manages its Clinical Immunology Clinic. He specializes in diseases of the immune system -- in particular, immunodeficiency diseases, such as human immunodeficiency virus (HIV) and other chronic... Read More →


Friday April 27, 2018 9:10am - 9:50am
TBA