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Saturday, April 28 • 4:00pm - 4:40pm
IL-6 in Health and Disease

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As a key cytokine regulator of innate and adaptive immunity, IL-6 plays complex and diverse pro- and anti-inflammatory roles, depending on the tissue in which it is expressed. The pivotal position of the IL-6 signaling pathway is exploited in many IMIDs, including RA and GSA, with elevated IL-6 levels often correlating with disease severity.

This lecture will highlight our evolving understanding of the contribution of IL-6 to the pathophysiology of IMIDs, and provide a clinical update on the targeted biologics that are beginning to emerge as a result. With multiple agents approved, seeking expanded approval, or under clinical investigation across a wide spectrum of IMIDs, inhibitors of the IL-6 pathway are poised to shape the future of IMID care. 

avatar for Prof. Dr. Stefan Rose-John

Prof. Dr. Stefan Rose-John

Director, Department of Biochemistry; Medical Faculty, Christian-Albrechts-University Kiel

Saturday April 28, 2018 4:00pm - 4:40pm